// RUN โ€” FITS

Can the AMD Instinct MI300X 192GB run DMPFold?

Yes โ€” here's how fast and up to what context, with real measured numbers.

DMPFold on the AMD Instinct MI300X 192GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 2672k 439342.1-536973.7 t/s ~3315.8-4052.6 (slow)
Q8 yes 2672k 878684.2-1073947.4 t/s ~6631.6-8105.3 (slow)
Q4 yes 2672k 1569078.9-1917763.2 t/s ~11842.1-14473.7 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI300X 192GB run DMPFold?โ–ถ

Yes. At Q4 it generates ~1569078.9-1917763.2 tok/s and fits up to 2672k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~11842.1-14473.7 tok/s.

How much context fits?โ–ถ

At Q4, up to about 2672k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.