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Can the AMD Instinct MI300X 192GB run HyenaDNA?
Yes — here's how fast and up to what context, with real measured numbers.
HyenaDNA on the AMD Instinct MI300X 192GB
| Quant | Fits? | Max context | Speed | Beyond context |
|---|---|---|---|---|
| FP16 | yes | 2672k | 252954.5-309166.7 t/s | ~1909.1-2333.3 (slow) |
| Q8 | yes | 2672k | 505909.1-618333.3 t/s | ~3818.2-4666.7 (slow) |
| Q4 | yes | 2672k | 903409.1-1104166.7 t/s | ~6818.2-8333.3 (slow) |
Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.
FAQ
Can the AMD Instinct MI300X 192GB run HyenaDNA?▶
Yes. At Q4 it generates ~903409.1-1104166.7 tok/s and fits up to 2672k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~6818.2-8333.3 tok/s.
How much context fits?▶
At Q4, up to about 2672k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.