// RUN โ€” FITS

Can the AMD Instinct MI300X 192GB run Mistral Medium 3.5?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Mistral Medium 3.5 on the AMD Instinct MI300X 192GB

QuantFits?Max contextSpeedBeyond context
FP16 no โ€” โ€” โ€”
Q8 yes 144k 26.1-31.9 t/s ~0.2-0.2 (slow)
Q4 yes 316k 46.6-56.9 t/s ~0.4-0.4 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI300X 192GB run Mistral Medium 3.5?โ–ถ

Yes. At Q4 it generates ~46.6-56.9 tok/s and fits up to 316k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.4-0.4 tok/s.

How much context fits?โ–ถ

At Q4, up to about 316k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.