// RUN โ€” FITS

Can the AMD Instinct MI300X 192GB run ProtRNA?

Yes โ€” here's how fast and up to what context, with real measured numbers.

ProtRNA on the AMD Instinct MI300X 192GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 2653k 2568.5-3139.2 t/s ~19.4-23.7 (slow)
Q8 yes 2663k 5136.9-6278.5 t/s ~38.8-47.4 (slow)
Q4 yes 2667k 9173.1-11211.5 t/s ~69.2-84.6 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI300X 192GB run ProtRNA?โ–ถ

Yes. At Q4 it generates ~9173.1-11211.5 tok/s and fits up to 2667k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~69.2-84.6 tok/s.

How much context fits?โ–ถ

At Q4, up to about 2667k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.