// RUN โ€” FITS

Can the AMD Instinct MI325X run DMPFold?

Yes โ€” here's how fast and up to what context, with real measured numbers.

DMPFold on the AMD Instinct MI325X

QuantFits?Max contextSpeedBeyond context
FP16 yes 3571k 497368.4-607894.7 t/s ~3315.8-4052.6 (slow)
Q8 yes 3571k 994736.8-1215789.5 t/s ~6631.6-8105.3 (slow)
Q4 yes 3571k 1776315.8-2171052.6 t/s ~11842.1-14473.7 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI325X run DMPFold?โ–ถ

Yes. At Q4 it generates ~1776315.8-2171052.6 tok/s and fits up to 3571k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~11842.1-14473.7 tok/s.

How much context fits?โ–ถ

At Q4, up to about 3571k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.