// RUN โ€” FITS

Can the AMD Instinct MI325X run ProtRNA?

Yes โ€” here's how fast and up to what context, with real measured numbers.

ProtRNA on the AMD Instinct MI325X

QuantFits?Max contextSpeedBeyond context
FP16 yes 3551k 2907.7-3553.8 t/s ~19.4-23.7 (slow)
Q8 yes 3561k 5815.4-7107.7 t/s ~38.8-47.4 (slow)
Q4 yes 3565k 10384.6-12692.3 t/s ~69.2-84.6 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI325X run ProtRNA?โ–ถ

Yes. At Q4 it generates ~10384.6-12692.3 tok/s and fits up to 3565k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~69.2-84.6 tok/s.

How much context fits?โ–ถ

At Q4, up to about 3565k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.