// RUN โ€” FITS

Can the AMD Instinct MI325X run Qwen2-72B?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Qwen2-72B on the AMD Instinct MI325X

QuantFits?Max contextSpeedBeyond context
FP16 yes 270k 26-31.8 t/s ~0.2-0.2 (slow)
Q8 yes 492k 52-63.5 t/s ~0.3-0.4 (slow)
Q4 yes 590k 92.8-113.5 t/s ~0.6-0.8 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI325X run Qwen2-72B?โ–ถ

Yes. At Q4 it generates ~92.8-113.5 tok/s and fits up to 590k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.6-0.8 tok/s.

How much context fits?โ–ถ

At Q4, up to about 590k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.