New: connect Claude & other AIs to GenAIList over MCP — research the catalog and contribute to the shared knowledge base. Learn how →
Can the AMD Instinct MI455X run HyenaDNA?
Yes — here's how fast and up to what context, with real measured numbers.
HyenaDNA on the AMD Instinct MI455X
| Quant | Fits? | Max context | Speed | Beyond context |
|---|---|---|---|---|
| FP16 | yes | 6041k | 935454.5-1143333.3 t/s | ~1909.1-2333.3 (slow) |
| Q8 | yes | 6041k | 1870909.1-2286666.7 t/s | ~3818.2-4666.7 (slow) |
| Q4 | yes | 6042k | 3340909.1-4083333.3 t/s | ~6818.2-8333.3 (slow) |
Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.
FAQ
Can the AMD Instinct MI455X run HyenaDNA?▶
Yes. At Q4 it generates ~3340909.1-4083333.3 tok/s and fits up to 6042k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~6818.2-8333.3 tok/s.
How much context fits?▶
At Q4, up to about 6042k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.