// RUN โ€” FITS

Can the AMD Instinct MI455X run OntoProtein?

Yes โ€” here's how fast and up to what context, with real measured numbers.

OntoProtein on the AMD Instinct MI455X

QuantFits?Max contextSpeedBeyond context
FP16 yes 6029k 14700-17966.7 t/s ~30-36.7 (slow)
Q8 yes 6035k 29400-35933.3 t/s ~60-73.3 (slow)
Q4 yes 6038k 52500-64166.7 t/s ~107.1-131 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI455X run OntoProtein?โ–ถ

Yes. At Q4 it generates ~52500-64166.7 tok/s and fits up to 6038k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~107.1-131 tok/s.

How much context fits?โ–ถ

At Q4, up to about 6038k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.