// RUN โ€” FITS

Can the AMD Instinct MI455X run Qwen2.5-72B?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Qwen2.5-72B on the AMD Instinct MI455X

QuantFits?Max contextSpeedBeyond context
FP16 yes 765k 84.9-103.8 t/s ~0.2-0.2 (slow)
Q8 yes 986k 169.8-207.6 t/s ~0.3-0.4 (slow)
Q4 yes 1084k 303.3-370.7 t/s ~0.6-0.8 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the AMD Instinct MI455X run Qwen2.5-72B?โ–ถ

Yes. At Q4 it generates ~303.3-370.7 tok/s and fits up to 1084k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.6-0.8 tok/s.

How much context fits?โ–ถ

At Q4, up to about 1084k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.