// RUN โ€” FITS

Can the AMD Ryzen AI Max+ 395 run DiffDock?

Yes โ€” here's how fast and up to what context, with real measured numbers.

DiffDock on the AMD Ryzen AI Max+ 395

QuantFits?Max contextSpeedBeyond context
FP16 yes 1734k 3984.2-4869.6 t/s ~155.6-190.2 (slow)
Q8 yes 1735k 7968.4-9739.1 t/s ~311.3-380.4 (slow)
Q4 yes 1735k 14229.2-17391.3 t/s ~555.8-679.3 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to SSD swap and speed drops to the "beyond" figure.

FAQ

Can the AMD Ryzen AI Max+ 395 run DiffDock?โ–ถ

Yes. At Q4 it generates ~14229.2-17391.3 tok/s and fits up to 1735k context; beyond that it spills to SSD swap and slows to ~555.8-679.3 tok/s.

How much context fits?โ–ถ

At Q4, up to about 1735k tokens stay in fast memory; longer context spills to SSD swap and throughput collapses.