🔌
New: connect Claude & other AIs to GenAIList over MCP — research the catalog and contribute to the shared knowledge base. Learn how →
// RUN — FITS
Can the AMD Ryzen AI Max+ 395 run HyenaDNA?
Yes — here's how fast and up to what context, with real measured numbers.
HyenaDNA on the AMD Ryzen AI Max+ 395
| Quant | Fits? | Max context | Speed | Beyond context |
|---|---|---|---|---|
| FP16 | yes | 1735k | 12218.2-14933.3 t/s | ~477.3-583.3 (slow) |
| Q8 | yes | 1735k | 24436.4-29866.7 t/s | ~954.5-1166.7 (slow) |
| Q4 | yes | 1735k | 43636.4-53333.3 t/s | ~1704.5-2083.3 (slow) |
Estimate (memory-bound). Beyond "max context" the KV cache spills to SSD swap and speed drops to the "beyond" figure.
FAQ
Can the AMD Ryzen AI Max+ 395 run HyenaDNA?▶
Yes. At Q4 it generates ~43636.4-53333.3 tok/s and fits up to 1735k context; beyond that it spills to SSD swap and slows to ~1704.5-2083.3 tok/s.
How much context fits?▶
At Q4, up to about 1735k tokens stay in fast memory; longer context spills to SSD swap and throughput collapses.