// RUN โ€” FITS

Can the Apple M1 Max 32GB run Nucleotide Transformer?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Nucleotide Transformer on the Apple M1 Max 32GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 340k 54.4-65.6 t/s ~1.4-1.6 (slow)
Q8 yes 378k 108.8-131.2 t/s ~2.7-3.3 (slow)
Q4 yes 395k 194.3-234.3 t/s ~4.9-5.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to SSD swap and speed drops to the "beyond" figure.

FAQ

Can the Apple M1 Max 32GB run Nucleotide Transformer?โ–ถ

Yes. At Q4 it generates ~194.3-234.3 tok/s and fits up to 395k context; beyond that it spills to SSD swap and slows to ~4.9-5.9 tok/s.

How much context fits?โ–ถ

At Q4, up to about 395k tokens stay in fast memory; longer context spills to SSD swap and throughput collapses.