// RUN — FITS

Can the Apple M2 Ultra 192GB run Nucleotide Transformer?

Yes — here's how fast and up to what context, with real measured numbers.

Nucleotide Transformer on the Apple M2 Ultra 192GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 2538k 108.8-131.2 t/s ~1.4-1.6 (slow)
Q8 yes 2576k 217.6-262.4 t/s ~2.7-3.3 (slow)
Q4 yes 2592k 388.6-468.6 t/s ~4.9-5.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to SSD swap and speed drops to the "beyond" figure.

→ All models on the Apple M2 Ultra 192GB → Nucleotide Transformer specs → Other hardware

FAQ

Can the Apple M2 Ultra 192GB run Nucleotide Transformer?▶

Yes. At Q4 it generates ~388.6-468.6 tok/s and fits up to 2592k context; beyond that it spills to SSD swap and slows to ~4.9-5.9 tok/s.

How much context fits?▶

At Q4, up to about 2592k tokens stay in fast memory; longer context spills to SSD swap and throughput collapses.