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Can the Instinct MI430X run DiffDock?
Yes — here's how fast and up to what context, with real measured numbers.
DiffDock on the Instinct MI430X
| Quant | Fits? | Max context | Speed | Beyond context |
|---|---|---|---|---|
| FP16 | yes | 6041k | 362623.5-443206.5 t/s | ~622.5-760.9 (slow) |
| Q8 | yes | 6041k | 725247-886413 t/s | ~1245.1-1521.7 (slow) |
| Q4 | yes | 6041k | 1295084-1582880.4 t/s | ~2223.3-2717.4 (slow) |
Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.
FAQ
Can the Instinct MI430X run DiffDock?▶
Yes. At Q4 it generates ~1295084-1582880.4 tok/s and fits up to 6041k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~2223.3-2717.4 tok/s.
How much context fits?▶
At Q4, up to about 6041k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.