// RUN โ€” FITS

Can the NVIDIA DGX Spark run DiffDock?

Yes โ€” here's how fast and up to what context, with real measured numbers.

DiffDock on the NVIDIA DGX Spark

QuantFits?Max contextSpeedBeyond context
FP16 yes 1734k 4923.2-5867.3 t/s ~180.3-214.9 (slow)
Q8 yes 1735k 9846.3-11734.7 t/s ~360.7-429.8 (slow)
Q4 yes 1735k 17582.8-20954.8 t/s ~644.1-767.6 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to SSD swap and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA DGX Spark run DiffDock?โ–ถ

Yes. At Q4 it generates ~17582.8-20954.8 tok/s and fits up to 1735k context; beyond that it spills to SSD swap and slows to ~644.1-767.6 tok/s.

How much context fits?โ–ถ

At Q4, up to about 1735k tokens stay in fast memory; longer context spills to SSD swap and throughput collapses.