// RUN โ€” FITS

Can the NVIDIA GeForce RTX 4080 run OntoProtein?

Yes โ€” here's how fast and up to what context, with real measured numbers.

OntoProtein on the NVIDIA GeForce RTX 4080

QuantFits?Max contextSpeedBeyond context
FP16 yes 189k 639.6-762.3 t/s ~34.8-41.4 (slow)
Q8 yes 195k 1279.2-1524.6 t/s ~69.5-82.9 (slow)
Q4 yes 198k 2284.4-2722.4 t/s ~124.1-148 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA GeForce RTX 4080 run OntoProtein?โ–ถ

Yes. At Q4 it generates ~2284.4-2722.4 tok/s and fits up to 198k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~124.1-148 tok/s.

How much context fits?โ–ถ

At Q4, up to about 198k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.