// RUN โ€” FITS

Can the NVIDIA GeForce RTX 5060 Ti 8GB run Nucleotide Transformer?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Nucleotide Transformer on the NVIDIA GeForce RTX 5060 Ti 8GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 13k 65.4-78 t/s ~5.8-7 (slow)
Q8 yes 51k 130.8-155.9 t/s ~11.7-13.9 (slow)
Q4 yes 68k 233.6-278.4 t/s ~20.9-24.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA GeForce RTX 5060 Ti 8GB run Nucleotide Transformer?โ–ถ

Yes. At Q4 it generates ~233.6-278.4 tok/s and fits up to 68k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~20.9-24.9 tok/s.

How much context fits?โ–ถ

At Q4, up to about 68k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.