// RUN โ€” FITS

Can the NVIDIA GeForce RTX 5080 run OntoProtein?

Yes โ€” here's how fast and up to what context, with real measured numbers.

OntoProtein on the NVIDIA GeForce RTX 5080

QuantFits?Max contextSpeedBeyond context
FP16 yes 189k 834.3-994.3 t/s ~34.8-41.4 (slow)
Q8 yes 195k 1668.6-1988.6 t/s ~69.5-82.9 (slow)
Q4 yes 198k 2979.6-3551 t/s ~124.1-148 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA GeForce RTX 5080 run OntoProtein?โ–ถ

Yes. At Q4 it generates ~2979.6-3551 tok/s and fits up to 198k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~124.1-148 tok/s.

How much context fits?โ–ถ

At Q4, up to about 198k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.