// RUN โ€” FITS

Can the NVIDIA GeForce RTX 5080 run ProteinLM?

Yes โ€” here's how fast and up to what context, with real measured numbers.

ProteinLM on the NVIDIA GeForce RTX 5080

QuantFits?Max contextSpeedBeyond context
FP16 yes 110k 116.8-139.2 t/s ~4.9-5.8 (slow)
Q8 yes 156k 233.6-278.4 t/s ~9.7-11.6 (slow)
Q4 yes 176k 417.1-497.1 t/s ~17.4-20.7 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA GeForce RTX 5080 run ProteinLM?โ–ถ

Yes. At Q4 it generates ~417.1-497.1 tok/s and fits up to 176k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~17.4-20.7 tok/s.

How much context fits?โ–ถ

At Q4, up to about 176k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.