// RUN โ€” FITS

Can the NVIDIA GeForce RTX 5090 run OntoProtein?

Yes โ€” here's how fast and up to what context, with real measured numbers.

OntoProtein on the NVIDIA GeForce RTX 5090

QuantFits?Max contextSpeedBeyond context
FP16 yes 414k 1557.3-1856 t/s ~34.8-41.4 (slow)
Q8 yes 420k 3114.7-3712 t/s ~69.5-82.9 (slow)
Q4 yes 423k 5561.9-6628.6 t/s ~124.1-148 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA GeForce RTX 5090 run OntoProtein?โ–ถ

Yes. At Q4 it generates ~5561.9-6628.6 tok/s and fits up to 423k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~124.1-148 tok/s.

How much context fits?โ–ถ

At Q4, up to about 423k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.