// RUN โ€” FITS

Can the NVIDIA L40S 48GB run OntoProtein?

Yes โ€” here's how fast and up to what context, with real measured numbers.

OntoProtein on the NVIDIA L40S 48GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 638k 750.9-894.9 t/s ~34.8-41.4 (slow)
Q8 yes 645k 1501.7-1789.7 t/s ~69.5-82.9 (slow)
Q4 yes 647k 2681.6-3195.9 t/s ~124.1-148 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA L40S 48GB run OntoProtein?โ–ถ

Yes. At Q4 it generates ~2681.6-3195.9 tok/s and fits up to 647k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~124.1-148 tok/s.

How much context fits?โ–ถ

At Q4, up to about 647k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.