// RUN โ€” FITS

Can the NVIDIA L40S 48GB run ProteinLM?

Yes โ€” here's how fast and up to what context, with real measured numbers.

ProteinLM on the NVIDIA L40S 48GB

QuantFits?Max contextSpeedBeyond context
FP16 yes 559k 105.1-125.3 t/s ~4.9-5.8 (slow)
Q8 yes 605k 210.2-250.6 t/s ~9.7-11.6 (slow)
Q4 yes 625k 375.4-447.4 t/s ~17.4-20.7 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA L40S 48GB run ProteinLM?โ–ถ

Yes. At Q4 it generates ~375.4-447.4 tok/s and fits up to 625k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~17.4-20.7 tok/s.

How much context fits?โ–ถ

At Q4, up to about 625k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.