// RUN โ€” FITS

Can the NVIDIA L40S 48GB run Qwen2.5-72B?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Qwen2.5-72B on the NVIDIA L40S 48GB

QuantFits?Max contextSpeedBeyond context
FP16 no โ€” โ€” โ€”
Q8 no โ€” โ€” โ€”
Q4 yes 6k 15.5-18.5 t/s ~0.7-0.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA L40S 48GB run Qwen2.5-72B?โ–ถ

Yes. At Q4 it generates ~15.5-18.5 tok/s and fits up to 6k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.7-0.9 tok/s.

How much context fits?โ–ถ

At Q4, up to about 6k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.