// RUN โ€” FITS

Can the NVIDIA RTX PRO 6000 Blackwell run Qwen2.5 Instruct (72B)?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Qwen2.5 Instruct (72B) on the NVIDIA RTX PRO 6000 Blackwell

QuantFits?Max contextSpeedBeyond context
FP16 no โ€” โ€” โ€”
Q8 yes 43k 18-21.4 t/s ~0.4-0.5 (slow)
Q4 yes 141k 32.1-38.3 t/s ~0.7-0.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA RTX PRO 6000 Blackwell run Qwen2.5 Instruct (72B)?โ–ถ

Yes. At Q4 it generates ~32.1-38.3 tok/s and fits up to 141k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.7-0.9 tok/s.

How much context fits?โ–ถ

At Q4, up to about 141k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.