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Can the AMD Radeon Pro W7900 48GB run DiffDock?
Yes — here's how fast and up to what context, with real measured numbers.
DiffDock on the AMD Radeon Pro W7900 48GB
| Quant | Fits? | Max context | Speed | Beyond context |
|---|---|---|---|---|
| FP16 | yes | 650k | 13446.6-16434.8 t/s | ~622.5-760.9 (slow) |
| Q8 | yes | 651k | 26893.3-32869.6 t/s | ~1245.1-1521.7 (slow) |
| Q4 | yes | 651k | 48023.7-58695.7 t/s | ~2223.3-2717.4 (slow) |
Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.
FAQ
Can the AMD Radeon Pro W7900 48GB run DiffDock?▶
Yes. At Q4 it generates ~48023.7-58695.7 tok/s and fits up to 651k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~2223.3-2717.4 tok/s.
How much context fits?▶
At Q4, up to about 651k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.