// RUN โ€” FITS

Can the NVIDIA B200 run Qwen2.5 Instruct (72B)?

Yes โ€” here's how fast and up to what context, with real measured numbers.

Qwen2.5 Instruct (72B) on the NVIDIA B200

QuantFits?Max contextSpeedBeyond context
FP16 yes 91k 40.2-47.9 t/s ~0.2-0.2 (slow)
Q8 yes 313k 80.3-95.7 t/s ~0.4-0.5 (slow)
Q4 yes 410k 143.4-171 t/s ~0.7-0.9 (slow)

Estimate (memory-bound). Beyond "max context" the KV cache spills to system RAM offload (depends on your system RAM) and speed drops to the "beyond" figure.

FAQ

Can the NVIDIA B200 run Qwen2.5 Instruct (72B)?โ–ถ

Yes. At Q4 it generates ~143.4-171 tok/s and fits up to 410k context; beyond that it spills to system RAM offload (depends on your system RAM) and slows to ~0.7-0.9 tok/s.

How much context fits?โ–ถ

At Q4, up to about 410k tokens stay in fast memory; longer context spills to system RAM offload (depends on your system RAM) and throughput collapses.